Digestive discomfort is one of the most common yet least understood challenges faced by people living with Ehlers-Danlos Syndrome (EDS), Pelvic Organ Prolapse, and Coeliac Disease. While these conditions may appear unrelated, they share surprising overlaps in how they affect the structure, movement, and function of the digestive system.
From sluggish motility and bloating to nutrient malabsorption and chronic fatigue, the gastrointestinal tract often reflects the deeper systemic stress caused by connective tissue weakness, autoimmune inflammation, or structural disruption. For many, this leads to a frustrating cycle of symptoms that traditional digestive remedies rarely address in full.
Yet, by understanding how these conditions interact and approaching gut care from both a medical and holistic perspective it becomes possible to restore comfort, improve digestion, and support the body’s natural balance.
This article explores the key digestive challenges faced in EDS, prolapse, and coeliac disease, the foundational management strategies that medical experts recommend, and the supportive role of natural supplements such as OxyTech, which can help ease constipation and fatigue without harsh irritation.
Whether you’ve been recently diagnosed or have lived with these conditions for years, this guide is designed to help you make informed, confident decisions about your digestive health rooted in science, supported by experience, and focused on long-term wellbeing.
The Complexities of Connective Tissue and Digestion

A. The Interconnectedness of Conditions
Digestive health can be profoundly affected by conditions that, at first glance, may seem unrelated such as Ehlers-Danlos Syndrome (EDS), pelvic organ prolapse, and coeliac disease. Yet all three share a common thread: disruption to the structure or function of the body’s connective and supportive tissues, which play a crucial role in maintaining digestive balance.
Ehlers-Danlos Syndrome (EDS):
EDS is a group of inherited connective tissue disorders characterised by joint hypermobility, fragile skin, and tissue laxity. Within the digestive system, weakened connective tissue can influence everything from the motility of the gut to the integrity of the intestinal walls. Many people with EDS experience symptoms such as reflux, bloating, constipation, or irritable bowel-like discomfort, all of which stem from reduced structural support within the gastrointestinal tract.
Prolapse:
Pelvic organ prolapse often occurs when the pelvic floor muscles and connective tissues can no longer support the bladder, uterus, or bowel effectively. In some individuals, this may develop secondary to the same connective tissue weakness seen in EDS. Prolapse can disrupt normal bowel movement and evacuation, contributing to constipation, incomplete emptying, and discomfort. Because the pelvic floor and lower bowel work together to regulate elimination, even mild prolapse can influence gut function and digestive comfort.
Coeliac Disease:
While not a connective tissue disorder, coeliac disease shares a significant overlap in gut vulnerability. This autoimmune condition triggers the body to attack the lining of the small intestine in response to gluten, leading to inflammation and villous atrophy (damage to the nutrient-absorbing surface). The result is malabsorption, fatigue, and chronic digestive symptoms. For those with underlying tissue fragility or pelvic dysfunction, coeliac disease can compound overall gut distress, requiring even greater care in management.
Together, these conditions highlight how interconnected the body truly is. Structural weakness, immune activation, and inflammation often coexist, creating a complex picture that demands a whole-body perspective on digestive care.
B. The Holistic Approach
Because these conditions interact at multiple physiological levels, medical management is essential and must always form the foundation of treatment. This may include:
- Dietary intervention: gluten-free diets for coeliac disease, fibre modification for prolapse or motility disorders.
- Pharmacological support: medications to aid motility, manage inflammation, or correct nutrient deficiencies.
- Physical or surgical treatment: pelvic floor physiotherapy, biofeedback, or surgical repair where appropriate.
Alongside these evidence-based therapies, nutritional supplements can play a supportive role helping to optimise tissue repair, reduce inflammation, and maintain digestive balance. However, they are not cures. Their value lies in complementing professional medical care, providing gentle support for the body’s healing processes, and improving quality of life when used under appropriate guidance.
A holistic plan that integrates medical, nutritional, and lifestyle interventions offers the most realistic and sustainable path to digestive stability in EDS, prolapse, and coeliac disease.
Condition-Specific Digestive Challenges & Management
Each of the conditions discussed, Ehlers-Danlos Syndrome (EDS), Pelvic Organ Prolapse (POP), and Coeliac Disease presents distinct yet sometimes overlapping digestive challenges. Understanding these unique mechanisms is key to creating a realistic and sustainable management plan.
A. Ehlers-Danlos Syndrome (EDS) and Hypermobility Spectrum Disorder (HSD)
Key Challenges
People with EDS or Hypermobility Spectrum Disorder often experience digestive symptoms that mirror structural and autonomic dysfunction elsewhere in the body. Because connective tissue is present throughout the gastrointestinal tract, weakened collagen can compromise both motility and stability.
- Motility Issues: Abnormal collagen can disrupt smooth muscle coordination, leading to gastroparesis (slow stomach emptying), slow transit constipation, or, conversely, rapid transit and diarrhoea. These irregularities make it difficult to predict digestion and absorption patterns.
- Dysautonomia and POTS (Postural Orthostatic Tachycardia Syndrome): Frequently coexisting with EDS, dysautonomia affects blood flow and nerve signalling to the digestive organs, slowing gastric emptying and altering bowel rhythm.
- Mast Cell Activation Syndrome (MCAS) and Food Sensitivities: Many individuals with EDS report heightened reactivity to foods, additives, and environmental triggers. MCAS can cause bloating, cramping, reflux, nausea, and histamine-related reactions, making diet management especially complex.
Foundational Management
While no single treatment addresses all aspects, a multidisciplinary approach provides the best results.
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Medication: Prokinetic agents (to support motility), anti-nausea medications, and occasionally low-dose neuromodulators can help reduce discomfort.
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Dietary Strategies:
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Small, frequent meals to ease digestive load.
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Low-FODMAP or low-histamine diets under the guidance of a registered dietitian, particularly where MCAS or bloating is an issue.
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Attention to hydration and electrolyte balance for those managing POTS-related symptoms.
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Physical Support: Gentle core and posture exercises from physiotherapists familiar with hypermobility can improve abdominal stability and gut motility.
B. Pelvic Organ Prolapse (POP) and Constipation
Key Challenges
Pelvic organ prolapse occurs when weakened or stretched pelvic tissues and muscles can no longer support the bladder, uterus, or bowel. In terms of digestion, the biggest issue is often obstructive defecation, where mechanical pressure disrupts normal bowel emptying.
- Obstructive Defecation: A rectocele (bulge in the rectal wall) can trap stool, leading to straining and a sensation of incomplete evacuation.
- Chronic Straining: Repeated straining, often due to constipation can worsen prolapse and perpetuate a cycle of pelvic floor dysfunction.
- Bowel Coordination: Poor synchronisation between abdominal pressure and pelvic floor relaxation can make bowel movements inefficient or painful.
Foundational Management
A targeted, pelvic floor-focused approach is essential.
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Pelvic Floor Physiotherapy: The cornerstone of management, focusing on muscle retraining, relaxation, and proper defecation technique. Biofeedback and electrical stimulation may assist in restoring coordination.
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Lifestyle Adjustments:
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Proper toilet posture, such as using a footstool or squatty potty, helps align the rectum for easier elimination.
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Hydration and adequate fibre intake (soluble fibre is usually best tolerated) reduce stool hardness and straining.
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Avoid excessive bearing down and instead focus on gentle, supported exhalation during bowel movements.
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Medical Interventions: In more severe cases, pessary devices or surgical repair may be considered to restore structural support.
C. Coeliac Disease
Key Challenges
Coeliac disease is an autoimmune disorder where gluten ingestion leads to immune-mediated damage of the small intestine’s lining. Over time, this causes villous atrophy, flattening of the villi that absorb nutrients and widespread nutritional deficiencies.
- Villous Atrophy: Gluten exposure triggers inflammation that destroys the villi, reducing the surface area available for absorption.
- Malabsorption: The resulting nutrient loss often leads to iron, B-vitamin, folate, calcium, and vitamin D deficiencies, contributing to fatigue, bone weakness, and poor tissue healing.
- Secondary Digestive Disturbances: After diagnosis, individuals may continue to experience bloating, altered motility, or lactose intolerance while the gut heals.
Foundational Management
The primary goal is to halt immune activity and restore nutrient absorption.
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Strict Gluten-Free Diet (GFD): The only effective treatment. Total avoidance of gluten found in wheat, barley, and rye allows the intestinal lining to regenerate. Cross-contamination control is critical for success.
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Nutrient Repletion:
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Supplementation of iron, B12, folate, and vitamin D as indicated by blood tests.
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Calcium and magnesium support may also be necessary for bone health.
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Monitoring and Follow-Up: Regular blood testing and sometimes repeat biopsies ensure full mucosal recovery and early detection of refractory disease.
Together, these three conditions show how structural, autoimmune, and mechanical factors can converge to challenge digestive function. Effective management begins with medical care, but a thoughtful combination of nutrition, movement, and lifestyle strategies can significantly improve gut comfort and quality of life.
Supplements for Symptom Management and Colon Cleansing

For individuals managing Ehlers-Danlos Syndrome (EDS), Pelvic Organ Prolapse, or Coeliac Disease, digestive symptoms such as constipation, bloating, and fatigue are among the most common and frustrating to live with. While medical treatment must always remain the foundation, the right supportive supplements can help restore balance, comfort, and energy when used responsibly and in conjunction with professional guidance.
A. OxyTech: A Colon Conditioning Approach
Product Overview
OxyTech is an oxygen-based colon conditioner formulated with magnesium and bioflavonoids. It is designed not as a stimulant laxative, but as a gentle, regenerative cleanser that supports normal bowel function and intestinal health.
Where traditional laxatives can “irritate your bowels to make them forcefully expel,” OxyTech works differently. It aims to regenerate the colon lining so that it functions normally. The formula gently releases activated oxygen in the digestive tract, helping to break down waste and debris for easy and comfortable elimination.
This approach promotes an aerobic intestinal environment that supports the growth of beneficial bacteria and contributes to an overall sense of digestive cleanliness and lightness without dependency or harsh side effects.
Potential Role in Digestive Symptom Management
OxyTech’s design makes it especially suitable for individuals whose digestion is sluggish or irregular:
- Constipation and Bloating: It acts as a non-laxative aid to encourage regular, comfortable bowel movements.
- Colon Lining Support: By oxygenating and cleansing the colon, it may help the digestive tract work more efficiently.
- Energy and Vitality: Magnesium contributes to normal energy-yielding metabolism and helps reduce tiredness and fatigue, symptoms frequently reported by people with EDS, prolapse, or coeliac disease.
Relevance to Specific Conditions
- EDS & Prolapse: Chronic, slow-transit constipation is a well-known challenge. Harsh laxatives can irritate the bowel and stress already fragile tissues. OxyTech provides a gentler alternative, supporting natural elimination without the cramping or urgency that many stimulant products cause.
- All Conditions: The magnesium component supports energy metabolism, muscular relaxation, and nerve function, making it relevant across all three conditions where fatigue, low energy, or digestive stagnation are common.
Usage Notes
- Take 1–2 capsules at least one hour after the final meal of the night.
- Drink plenty of water to activate the formula and support cleansing.
- Adjust dosage gradually and maintain for a minimum of 10 days before transitioning to a daily maintenance level.
- OxyTech is generally considered compatible with most medications, including antibiotics.
- As with all supplements, those who are pregnant, breastfeeding, or on prescription medication should seek medical advice before use.
B. Other General Supportive Supplements (The EDS/Prolapse/Coeliac Overlap)
The following nutrients and compounds are commonly recommended to complement medical care and support digestive resilience across all three conditions.
Collagen Support (EDS / Prolapse)
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Vitamin C, Zinc, and Copper, all present or complementary to OxyTech’s formula are essential cofactors for collagen synthesis. Supporting collagen production can help strengthen connective tissue integrity, benefiting both gut structure and pelvic stability.
Gut Lining Repair (Coeliac / EDS)
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L-Glutamine is the primary fuel for intestinal cells (enterocytes) and may assist in repairing the intestinal lining. While it cannot replace the need for a strict gluten-free diet in coeliac disease, it may help soothe inflammation and promote mucosal healing once gluten has been eliminated.
Motility Support (EDS / Prolapse)
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Magnesium, in its various forms, can help soften stools and promote smooth muscle relaxation, easing bowel movements without the irritation associated with stimulant laxatives. Its presence in OxyTech further enhances its value as a supportive tool for sluggish digestion.
Digestive Enzymes (All Conditions)
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Digestive enzyme supplements assist in breaking down food into smaller, more absorbable molecules. This can reduce bloating, discomfort, and malabsorption, particularly helpful for those whose gut lining or motility has been compromised.
Together, these supplements form a supportive framework for managing digestive symptoms common to EDS, prolapse, and coeliac disease. They work best when used as part of a comprehensive plan that includes medical supervision, balanced nutrition, and attention to hydration and lifestyle.
Critical Considerations and Safety
Supporting digestive health in complex conditions such as Ehlers-Danlos Syndrome (EDS), Pelvic Organ Prolapse, and Coeliac Disease requires careful attention to safety, medical supervision, and product quality. While supplements can play a valuable role in improving comfort and overall wellbeing, they should always be used with informed, professional guidance.
A. The Importance of Professional Guidance
Both EDS and Coeliac Disease demand formal diagnosis and ongoing medical management by qualified specialists such as geneticists, gastroenterologists, and dietitians. These professionals ensure accurate assessment, appropriate treatment, and monitoring for related complications.
Before starting any supplement including OxyTech, it is essential to consult with your healthcare provider, especially if you:
- Are managing complex medical conditions
- Take prescription medication
- Are pregnant or breastfeeding
- Are considering supplementation for a child (OxyTech may be used for children aged 7 years and over, as advised by the manufacturer)
Professional guidance ensures that supplements are chosen appropriately and safely integrated into a broader treatment plan.
B. Supplement Quality and Purity
When selecting supplements, quality assurance is vital, especially for individuals with coeliac disease or heightened immune sensitivity.
- Coeliac Alert: Always verify that supplements are certified gluten-free to prevent accidental exposure or cross-contamination, which can trigger intestinal inflammation and reverse progress toward healing.
- Manufacturing Standards: OxyTech is produced to Good Manufacturing Practice (GMP) standards, ensuring purity, consistency, and quality. It is also Kosher-certified, reflecting strict product integrity and careful ingredient sourcing.
Choosing supplements from reputable, transparent manufacturers minimises the risk of contamination and guarantees a higher level of product safety.
C. Disclaimer
This article is intended for informational and educational purposes only. It is not designed to diagnose, treat, cure, or prevent any disease. All supplement and lifestyle recommendations are based on general principles of digestive and connective tissue support and should not replace medical advice from a qualified professional.
Dulwich Health Ltd. provides natural health products as complementary tools to support wellbeing, always encouraging users to work collaboratively with their healthcare team.
Beyond Supplements
While supplements can offer meaningful support, true digestive balance depends on the everyday habits that nurture the body as a whole. For individuals living with Ehlers-Danlos Syndrome (EDS), Pelvic Organ Prolapse, or Coeliac Disease, small, consistent lifestyle choices can make a lasting difference in comfort, energy, and quality of life.
The Role of Lifestyle
- Stress Management: Chronic stress can slow digestion, heighten inflammation, and worsen gastrointestinal symptoms. Gentle relaxation techniques such as deep breathing, mindfulness, yoga, or guided meditation can help calm both the nervous system and the digestive tract.
- Gentle Exercise: For those with EDS or prolapse, maintaining mobility and core strength is important, but activities must be chosen with care. Low-impact movement such as walking, swimming, Pilates, or tailored physiotherapy exercises can improve circulation and digestion without overstraining joints or pelvic tissues.
- Consistent Hydration: Adequate water intake supports healthy bowel movements, tissue elasticity, and overall digestive function. For people using OxyTech or managing constipation, hydration is particularly vital to aid natural elimination.
Taking an Active, Informed Role
Managing these complex conditions can be challenging, but progress begins with understanding and empowerment. By combining medical care, appropriate nutrition, mindful supplementation, and balanced lifestyle habits, it’s possible to reduce discomfort, improve digestion, and restore confidence in your body’s resilience.
Each positive step whether it’s refining your diet, adjusting your exercise, or choosing a cleaner supplement builds towards better health over time. With knowledge, patience, and professional support, you can create a plan that works uniquely for you and supports both gut health and overall wellbeing.
Digestive Health in EDS, Prolapse and Coeliac Disease
Click a question to reveal a concise, trustworthy answer.
Why do people with EDS often have digestive problems?
Connective tissue supports the entire gut. In EDS and HSD, collagen differences can affect motility and stability, leading to reflux, bloating, constipation or rapid transit.
How does pelvic organ prolapse affect bowel movements?
Prolapse can cause obstructive defecation. A rectocele may trap stool, which leads to straining and a feeling of incomplete emptying. Pelvic floor physio is first line care.
What makes coeliac disease different from food sensitivity or IBS?
Coeliac is an autoimmune disease. Gluten damages the small intestine villi and causes malabsorption. A strict gluten free diet is essential, not optional.
Can OxyTech help with constipation without acting like a stimulant laxative?
OxyTech is described as an oxygen based colon conditioner. It aims to gently break down debris and support a healthy environment, rather than irritate the bowel to force expulsion.
How should OxyTech be taken safely and who should avoid it?
- Start with 1 to 2 capsules at least one hour after the last meal of the night.
- Drink plenty of water and adjust for maintenance after at least 10 days.
- Speak to your clinician if pregnant or breastfeeding. For children, the manufacturer advises from age 7 and over.
Is OxyTech compatible with medicines and antibiotics?
The manufacturer indicates it can be taken with most medicines, including antibiotics. Always check with your doctor for your specific case.
What supplements commonly support the overlap of EDS, prolapse and coeliac symptoms?
- L-glutamine for gut lining support.
- Magnesium for motility and energy metabolism.
- Digestive enzymes to aid breakdown and absorption.
- Vitamin C, zinc and copper as collagen cofactors for tissue integrity.
What diet steps help with prolapse related constipation and straining risk?
Use proper toilet posture with a footstool, keep stools soft with hydration and soluble fibre, and avoid bearing down. Pelvic floor physio can retrain technique and coordination.
For coeliac disease, how do I avoid accidental gluten in supplements?
Choose supplements that are certified gluten free and check for cross contamination policies. This helps protect healing and prevents setbacks.
Could MCAS or histamine issues change my diet or supplement plan in EDS or HSD?
Yes. Some benefit from a short term low histamine approach and careful product selection. Work with a clinician or dietitian to tailor and reintroduce foods safely.
What non supplement steps support digestion across these conditions?
Gentle movement, stress reduction, meal timing, thorough chewing, and steady hydration support motility and comfort. These are the daily foundations.
When should I see a specialist rather than self manage with supplements only?
If you have red flags such as unintentional weight loss, bleeding, persistent vomiting, severe pain, fever, or if symptoms do not improve. EDS and coeliac require specialist care.
Educational content only. Not medical advice. Always speak with your healthcare professional before starting supplements or changing medication. Product information may reflect testimonials and practical experience. Individual results vary.
Research References
Key scientific and clinical sources that informed this article.
Ehlers-Danlos Syndrome (EDS) & Digestive Function
GI manifestations associated with Ehlers-Danlos Syndrome
EDS Society: Gastrointestinal disorders in EDS
Connective tissue disorders and GI complications
Overlap between EDS, POTS and dysautonomia
Mast Cell Activation Syndrome (MCAS) and digestive symptoms
Pelvic Organ Prolapse & Bowel Dysfunction
Pelvic floor disorders and bowel dysfunction
Impact of pelvic organ prolapse on bowel movements
NHS: Pelvic organ prolapse overview and treatment
Defecatory dysfunction in pelvic floor disorders
Coeliac Disease (Pathology, Management & Nutrition)
Pathophysiology and diagnosis of coeliac disease
Nutritional considerations and gluten-free management
NHS: Coeliac disease guidance and care
Coeliac Foundation: What gluten is and why it matters
Constipation, Motility Disorders & Slow Transit
Pathways and causes of chronic constipation
Motility disorders and GI transit problems
Slow-transit constipation mechanisms and interventions
Magnesium, Energy & Digestive Function (OxyTech-Relevant)
NIH: Magnesium roles in energy and digestion
Magnesium and bowel motility research
Magnesium and muscle function in GI motility
Gut Lining Support, L-Glutamine & Mucosal Repair
Glutamine’s role in gut lining and barrier repair
Effects of glutamine supplementation on mucosal integrity
General Digestive Health in Chronic Conditions
GI symptoms and management in chronic disorders
Digestive function and systemic chronic illness